Drug Category:
Cholesterol
Brand Name:
Crestor
Generic Name:
Rosuvastatin
About Crestor
(Rosuvastatin):
Brand name:
Crestor Generic name: Rosuvastatin What is the most
important information I should know about Crestor?
• Rare cases of muscle problems and liver problems
have been associated with the use of Crestor and other
similar medicines. Contact your doctor immediately
if you experience unexplained muscle pain tenderness
or weakness especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes
abdominal pain unexplained fatigue dark colored urine
or pale colored stools. These may be early symptoms
of muscle or liver problems. • Crestor is in the FDA
pregnancy category X. This means that Crestor is known
to cause birth defects in an unborn baby when taken
during pregnancy. Do not take Crestor if you are pregnant
or could become pregnant during treatment. • Do not
take Crestor without first talking to your doctor
if you have liver disease. • Crestor and other similar
medicines can cause muscle injury which in rare severe
cases can cause kidney damage and organ failure that
are potentially life-threatening. • Alcohol and Crestor
can both be damaging to the liver. Discuss with your
doctor the amount of alcohol that you drink so that
it can be determined if Crestor is the best choice
for lowering your cholesterol. What is Crestor? •
Crestor is an HMG CoA reductase inhibitor. Crestor
blocks the production of cholesterol (a type of fat)
in the body. • Crestor is used to reduce the amounts
of LDL (bad) cholesterol total cholesterol triglycerides
(another type of fat) and apolipoprotein B (a protein
needed to make cholesterol) in the blood. Crestor
also increases the level of HDL (good) cholesterol
in the blood. These actions are important in reducing
the risk of atherosclerosis (fatty deposits in the
arteries) which can lead to heart attack stroke and
peripheral vascular disease. • Crestor may also be
used for purposes other than those listed in this
medication guide. What should I discuss with my healthcare
provider before taking Crestor? • Do not take Crestor
without first talking to your doctor if you have liver
disease. • Before taking Crestor tell your doctor
if you have kidney problems; have hypothyroidism (low
thyroid function); drink alcoholic beverages; have
a chronic muscular disease; require major surgery;
or have a blood disorder. • You may not be able to
take Crestor or you may require a dosage adjustment
or special monitoring during treatment if you have
any of the conditions listed above. • Crestor and
other similar medicines can cause muscle injury which
in rare severe cases can cause kidney damage and organ
failure that are potentially life-threatening. • Crestor
is in the FDA pregnancy category X. This means that
Crestor is known to cause birth defects in an unborn
baby when taken during pregnancy. Do not take Crestor
if you are pregnant or could become pregnant during
treatment. • It is not known whether Crestor passes
into breast milk and if it will be harmful to a nursing
baby. Do not take this medication without first talking
to your doctor if you are breast-feeding a baby. How
should I take Crestor? • Take Crestor exactly as directed
by your doctor. If you do not understand these directions
ask your pharmacist nurse or doctor to explain them
to you. • Take each dose with a full glass of water.
• Crestor can be taken with or without food. • Crestor
is usually taken once a day. Try to take each dose
at the same time daily. Follow your doctor's instructions.
• It is important to take Crestor regularly to get
the most benefit. Do not stop taking Crestor without
first talking to your doctor. It may be weeks or months
before beneficial effects are seen from this medication.
• Your doctor may want to monitor your liver function
with blood tests before starting treatment with Crestor
at twelve weeks after start of treatment and after
any increase in dose and periodically (every 6 months)
thereafter. Depending on the results of these tests
your doctor can determine how much monitoring you
will require. • Eat a low-fat low-cholesterol diet.
To realize beneficial effects from Crestor avoid fatty
high-cholesterol foods. • Store Crestor at room temperature
away from moisture and heat. What happens if I miss
a dose? • Take the missed dose as soon as you remember.
However if it is almost time for the next dose skip
the missed dose and take only the next regularly scheduled
dose. Do not take a double dose of this medication.
What happens if I overdose? • Seek emergency medical
attention if an overdose is suspected. • The symptoms
of a Crestor overdose are not known. What should I
avoid while taking Crestor? • Alcohol and Crestor
can both be damaging to the liver. Discuss with your
doctor the amount of alcohol that you drink so that
it can be determined if Crestor is the best choice
for lowering your cholesterol. • Do not take Crestor
with antacids that contain aluminum and magnesium
such as Maalox Mylanta Gelusil and others. If an antacid
that contains aluminum and magnesium is needed it
should be taken at least 2 hours following a dose
of Crestor. What are the possible side effects of
Crestor? • Rare cases of muscle problems and liver
problems have been associated with the use of Crestor
and other similar medicines. Contact your doctor immediately
if you experience unexplained muscle pain tenderness
or weakness especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes
abdominal pain unexplained fatigue dark colored urine
or pale colored stools. These may be early symptoms
of muscle or liver problems. • If you experience a
rare but serious allergic reaction (difficulty breathing;
closing of the throat; swelling of the lips tongue
or face; or hives) stop taking Crestor and seek emergency
medical attention or contact your doctor immediately.
• Other less serious side effects may be more likely
to occur. Continue to take Crestor and talk to your
doctor if you experience headache; diarrhea or constipation;
or nausea or upset stomach. • Side effects other than
those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is
especially bothersome. What other drugs will affect
Crestor? • Do not take Crestor with antacids that
contain aluminum and magnesium such as Maalox Mylanta
Gelusil and others. If an antacid that contains aluminum
and magnesium is needed it should be taken at least
2 hours following a dose of Crestor. • Before taking
Crestor talk to your doctor if you are taking any
of the following medicines: cyclosporine (Sandimmune
Neoral); clofibrate (Atromid-S); fenofibrate (Tricor);
gemfibrozil (Lopid); niacin (Nicolar Nicobid Nicotinex
others); or warfarin (Coumadin). • You may require
a dosage adjustment or special monitoring during treatment
if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact
with Crestor. Talk to your doctor and pharmacist before
taking any prescription or over-the-counter medicines
including vitamins minerals and herbal products.
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